Есть решение, проверено на Server2019

Разрешает изменение масштаба для всего сервера:
Goto „HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Terminal Server\WinStations\IgnoreClientDesktopScaleFactor“ =>
if IgnoreClientDesktopScaleFactor does not exist then create a new DWORD-value =>
Type in Decimal Value: Turn on 1 (Turn off 0)

Выбор масштаба для текущего пользователя:
Goto „HKEY_CURRENT_USER\Control Panel\Desktop\LogPixels“ =>
if LogPixels does not exist then create a new DWORD-value =>
Type in Decimal Value:
96 for Smaller 100%
120 for Medium 125%
144 for Larger 150%







И батник для удобства пользователей:

cls

@echo off

color 0e

echo.

echo Choose a desired scale from the list.

echo.

echo Enter 96 for 100%%

echo Enter 120 for 125%%

echo Enter 144 for 150%%

echo Enter 192 for 200%% (Good for 4K monitors)

echo Enter 288 for 300%% (Good for Surface Tablets where someone normally needs 150%%)

echo Enter 384 for 400%% (Cannot think of any ideal use for this.)

echo.

set /p scale=Set the number from the table above for the desired zoom scale:

reg add "HKCU\Control Panel\Desktop" /v LogPixels /t REG_DWORD /d %scale% /f

echo.

echo You must log off in order for the settings to apply. Close all programs and pause

logoff